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KMID : 0615720100270060011
Jouranl of Korean Acupuncture and Moxibustion society
2010 Volume.27 No. 6 p.11 ~ p.21
Clinical Study of Acupuncture Theraphy of Gastrointestinal Side Effect of Levodopa: Focused on Idiopathic Pakinson¡¯s Disease Patients
Yang Dong-Ho

Lee Kyung-Yun
Shin Hyun-Seung
Cho Song-Hyun
Lim Chang-Sun
Yim Jun-Hyok
Yun Suk-Hoon
Lee Han
Kang Myung-Jin
Abstract
Objective: This study was aimed at investigating the therapeutic effects of acupuncture on gastrointestinal side effect of Levodopa on idiopathic Pakinson¡¯s disease patients.

Methods: The subjects of this study were 42 patients with idiopathic Parkinson¡¯s disease. We divided them into two groups; acupuncture treatment group, no treatment group. We treated the former group with acupuncture therapy focusing on gastrointestinal side effect of Levodopa while administering Levodopa as well. And the latter group was also dosed up with Levodopa without acupuncture therapy. To see the effect of acupuncture treatment clearly, we used gastrointestinal syndrome rating scale (GSRS) and visual analog scale (VAS) and compared the GSRS grade and VAS score of two groups statistically, after 1, 2, 3, 4 weeks since they have been under the treatment.

Results: This study suggests that the group who has been treated with acupuncture on gastroin- testinal side effect of Levodopa on idiopathic pakinson¡¯s disease patients showed higher GSRS grade and VAS score than the one that has not. But, We could¡¯t find statistical significance between the two groups on improvement of GSRS grade and VAS score.

Conclusions: These results proved that acupucture theraphy might be available for relieving symptoms related with gastrointestinal side effect of Levodopa than the one that has not. But further studies are necessary.
KEYWORD
Parkinson¡¯s disease, Levodopa, Acupuncture therapy, Oriental and Western medical Treat- ment
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